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Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons

Mitochondrial DNA (mtDNA) deletions have been investigated in a number of neurodegenerative diseases. This study aimed to investigate the characteristics of mtDNA deletions found in single substantia nigra neurons from three patient groups: controls, Parkinson disease patients, and a patient with Pa...

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Detalhes bibliográficos
Main Authors: Reeve, Amy K., Krishnan, Kim J., Elson, Joanna L., Morris, Christopher M., Bender, Andreas, Lightowlers, Robert N., Turnbull, Douglass M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253975/
https://ncbi.nlm.nih.gov/pubmed/18179904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.09.018
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