Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation

Expression QTL (eQTL) detection has emerged as an important tool for unraveling the relationship between genetic risk factors and disease or clinical phenotypes. Most studies are predicated on the assumption that only a single causal variant explains the association signal in each interval. This gre...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Zeng, Biao, Lloyd-Jones, Luke R., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Franke, Lude, Vosa, Urmo, Claringbould, Annique, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E., Gibson, Greg
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2019
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614888/
https://ncbi.nlm.nih.gov/pubmed/31123039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302091
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