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PolyQTL: Bayesian multiple eQTL detection with control for population structure and sample relatedness

MOTIVATION: Expression quantitative loci (eQTL) are being used widely to annotate and interpret GWAS hits. Recent studies have demonstrated that individual gene expression is often regulated by multiple independent cis-acting eQTL. Diverse methods, frequentist and Bayesian, have already been develop...

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Enregistré dans:
Détails bibliographiques
Publié dans:Bioinformatics
Auteurs principaux: Zeng, Biao, Gibson, Greg
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419993/
https://ncbi.nlm.nih.gov/pubmed/30165584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty728
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