Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation

Expression QTL (eQTL) detection has emerged as an important tool for unraveling the relationship between genetic risk factors and disease or clinical phenotypes. Most studies are predicated on the assumption that only a single causal variant explains the association signal in each interval. This gre...

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Detalles Bibliográficos
Publicado en:Genetics
Autores principales: Zeng, Biao, Lloyd-Jones, Luke R., Montgomery, Grant W., Metspalu, Andres, Esko, Tonu, Franke, Lude, Vosa, Urmo, Claringbould, Annique, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E., Gibson, Greg
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614888/
https://ncbi.nlm.nih.gov/pubmed/31123039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302091
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