Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression

Expression quantitative trait locus (eQTL) detection has emerged as an important tool for unraveling of the relationship between genetic risk factors and disease or clinical phenotypes. Most studies use single marker linear regression to discover primary signals, followed by sequential conditional m...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Zeng, Biao, Lloyd-Jones, Luke R., Holloway, Alexander, Marigorta, Urko M., Metspalu, Andres, Montgomery, Grant W., Esko, Tonu, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E., Gibson, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555460/
https://ncbi.nlm.nih.gov/pubmed/28600440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.043752
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