Constraints on eQTL Fine Mapping in the Presence of Multisite Local Regulation of Gene Expression

Expression quantitative trait locus (eQTL) detection has emerged as an important tool for unraveling of the relationship between genetic risk factors and disease or clinical phenotypes. Most studies use single marker linear regression to discover primary signals, followed by sequential conditional m...

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Enregistré dans:
Détails bibliographiques
Publié dans:G3 (Bethesda)
Auteurs principaux: Zeng, Biao, Lloyd-Jones, Luke R., Holloway, Alexander, Marigorta, Urko M., Metspalu, Andres, Montgomery, Grant W., Esko, Tonu, Brigham, Kenneth L., Quyyumi, Arshed A., Idaghdour, Youssef, Yang, Jian, Visscher, Peter M., Powell, Joseph E., Gibson, Greg
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2017
Sujets:
Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555460/
https://ncbi.nlm.nih.gov/pubmed/28600440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.043752
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