Effect of Cryopreservation on Autologous Chimeric Antigen Receptor T Cell Characteristics

As clinical applications for chimeric antigen receptor T cell (CART) therapy extend beyond early phase trials, commercial manufacture incorporating cryopreservation steps becomes a logistical necessity. The effect of cryopreservation on CART characteristics is unclear. We retrospectively evaluated t...

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Publicado en:Mol Ther
Main Authors: Panch, Sandhya R., Srivastava, Sandeep K., Elavia, Nasha, McManus, Andrew, Liu, Shutong, Jin, Ping, Highfill, Steven L., Li, Xiaobai, Dagur, Pradeep, Kochenderfer, James N., Fry, Terry J., Mackall, Crystal L., Lee, Daniel, Shah, Nirali N., Stroncek, David F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Gene & Cell Therapy 2019
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612799/
https://ncbi.nlm.nih.gov/pubmed/31178392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.05.015
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