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In Vivo Metabolism of Ibuprofen in Growing Conventional Pigs: A Pharmacokinetic Approach
The juvenile conventional pig has been suggested as a preclinical animal model to evaluate pharmacokinetic (PK), pharmacodynamic (PD), and safety parameters in children. However, a lot of developmental changes in pig physiology still need to be unraveled. While the in vitro ontogeny of pig biotransf...
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| Publicado en: | Front Pharmacol |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610244/ https://ncbi.nlm.nih.gov/pubmed/31316382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00712 |
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