The Ontogeny of Cytochrome P450 Enzyme Activity and Protein Abundance in Conventional Pigs in Support of Preclinical Pediatric Drug Research

Since the implementation of several legislations to improve pediatric drug research, more pediatric clinical trials are being performed. In order to optimize these pediatric trials, adequate preclinical data are necessary, which are usually obtained by juvenile animal models. The growing piglet has...

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Опубликовано в: :Front Pharmacol
Главные авторы: Millecam, Joske, De Clerck, Laura, Govaert, Elisabeth, Devreese, Mathias, Gasthuys, Elke, Schelstraete, Wim, Deforce, Dieter, De Bock, Lies, Van Bocxlaer, Jan, Sys, Stanislas, Croubels, Siska
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960725/
https://ncbi.nlm.nih.gov/pubmed/29867477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00470
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