The Ontogeny of Cytochrome P450 Enzyme Activity and Protein Abundance in Conventional Pigs in Support of Preclinical Pediatric Drug Research

Since the implementation of several legislations to improve pediatric drug research, more pediatric clinical trials are being performed. In order to optimize these pediatric trials, adequate preclinical data are necessary, which are usually obtained by juvenile animal models. The growing piglet has...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Millecam, Joske, De Clerck, Laura, Govaert, Elisabeth, Devreese, Mathias, Gasthuys, Elke, Schelstraete, Wim, Deforce, Dieter, De Bock, Lies, Van Bocxlaer, Jan, Sys, Stanislas, Croubels, Siska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960725/
https://ncbi.nlm.nih.gov/pubmed/29867477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00470
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