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In Vivo Metabolism of Ibuprofen in Growing Conventional Pigs: A Pharmacokinetic Approach

The juvenile conventional pig has been suggested as a preclinical animal model to evaluate pharmacokinetic (PK), pharmacodynamic (PD), and safety parameters in children. However, a lot of developmental changes in pig physiology still need to be unraveled. While the in vitro ontogeny of pig biotransf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Joske Millecam, Siegrid De Baere, Siska Croubels, Mathias Devreese
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019-06-01
Cyfres:Frontiers in Pharmacology
Pynciau:
pig
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fphar.2019.00712/full
Tagiau: Ychwanegu Tag
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