Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model

Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of the drug. Recently, the conventional growing p...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: Millecam, Joske, van Bergen, Thomas, Schauvliege, Stijn, Antonissen, Gunther, Martens, Ann, Chiers, Koen, Gehring, Ronette, Gasthuys, Elke, Vande Walle, Johan, Croubels, Siska, Devreese, Mathias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://ncbi.nlm.nih.gov/pubmed/31143123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00505
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