Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model

Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of the drug. Recently, the conventional growing p...

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Spremljeno u:
Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Millecam, Joske, van Bergen, Thomas, Schauvliege, Stijn, Antonissen, Gunther, Martens, Ann, Chiers, Koen, Gehring, Ronette, Gasthuys, Elke, Vande Walle, Johan, Croubels, Siska, Devreese, Mathias
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://ncbi.nlm.nih.gov/pubmed/31143123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00505
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