Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model

Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of the drug. Recently, the conventional growing p...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Millecam, Joske, van Bergen, Thomas, Schauvliege, Stijn, Antonissen, Gunther, Martens, Ann, Chiers, Koen, Gehring, Ronette, Gasthuys, Elke, Vande Walle, Johan, Croubels, Siska, Devreese, Mathias
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://ncbi.nlm.nih.gov/pubmed/31143123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00505
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