Developmental Pharmacokinetics and Safety of Ibuprofen and Its Enantiomers in the Conventional Pig as Potential Pediatric Animal Model

Pediatric drug development, especially in disease areas that only affect children, can be stimulated by using juvenile animal models not only for general safety studies, but also to gain knowledge on the pharmacokinetic and pharmacodynamic properties of the drug. Recently, the conventional growing p...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Millecam, Joske, van Bergen, Thomas, Schauvliege, Stijn, Antonissen, Gunther, Martens, Ann, Chiers, Koen, Gehring, Ronette, Gasthuys, Elke, Vande Walle, Johan, Croubels, Siska, Devreese, Mathias
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521589/
https://ncbi.nlm.nih.gov/pubmed/31143123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00505
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