Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

Recent findings suggest that tau oligomers, which form before neurofibrillary tangles (NFTs), are the true neurotoxic tau entities in neurodegenerative tauopathies, including Alzheimer's disease (AD). Studies in animal models of tauopathy suggest that tau oligomers play a key role in eliciting...

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Argitaratua izan da:J Neurosci
Egile Nagusiak: Castillo-Carranza, Diana L., Sengupta, Urmi, Guerrero-Muñoz, Marcos J., Lasagna-Reeves, Cristian A., Gerson, Julia E., Singh, Gurpreet, Estes, D. Mark, Barrett, Alan D. T., Dineley, Kelly T., Jackson, George R., Kayed, Rakez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608097/
https://ncbi.nlm.nih.gov/pubmed/24647946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3192-13.2014
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