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Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages
The Fanconi anemia proteins participate in a canonical pathway that repairs cross‐linking agent‐induced DNA damage. Cells with inactivated Fanconi anemia genes are universally hypersensitive to such agents. Fanconi anemia‐deficient hematopoietic stem cells are also hypersensitive to inflammatory cyt...
Kaydedildi:
| Yayımlandı: | J Leukoc Biol |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608044/ https://ncbi.nlm.nih.gov/pubmed/26432900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-201R |
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