c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into functional proteins. Specifically, MYC drives the translation of most protein components of the electron transport chain...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Singh, Kamini, Lin, Jianan, Zhong, Yi, Burčul, Antonija, Mohan, Prathibha, Jiang, Man, Sun, Liping, Yong-Gonzalez, Vladimir, Viale, Agnes, Cross, Justin R., Hendrickson, Ronald C., Rätsch, Gunnar, Ouyang, Zhengqing, Wendel, Hans-Guido
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605752/
https://ncbi.nlm.nih.gov/pubmed/31142587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181726
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