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NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy
SIMPLE SUMMARY: eIF4A-targeted translational inhibitors, such as silvestrol and its analogues, have emerged as strong anticancer therapies. Here, we tested the efficacy of eIF4A inhibition across a large and diverse panel of cancer cell lines and found B cell lymphomas to be the most sensitive group...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7915661/ https://ncbi.nlm.nih.gov/pubmed/33562682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13040639 |
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