The oncogenic action of NRF2 depends on de-glycation by Fructosamine-3-kinase

The NRF2 transcription factor controls a cell stress program that is implicated in cancer and there is great interest in targeting NRF2 for therapy. We show that NRF2 activity depends on Fructosamine-3-kinase (FN3K) - a kinase that triggers protein de-glycation. In its absence, NRF2 is extensively g...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell
मुख्य लेखकों: Sanghvi, Viraj R., Leibold, Josef, Mina, Marco, Mohan, Prathibha, Berishaj, Marjan, Li, Zhuoning, Miele, Matthew M., Lailler, Nathalie, Zhao, Chunying, de Stanchina, Elisa, Viale, Agnes, Akkari, Leila, Lowe, Scott W., Ciriello, Giovanni, Hendrickson, Ronald C., Wendel, Hans-Guido
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2019
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693658/
https://ncbi.nlm.nih.gov/pubmed/31398338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.07.031
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन