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c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma
The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into functional proteins. Specifically, MYC drives the translation of most protein components of the electron transport chain...
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| Published in: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605752/ https://ncbi.nlm.nih.gov/pubmed/31142587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181726 |
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