c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into functional proteins. Specifically, MYC drives the translation of most protein components of the electron transport chain...

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Vydáno v:J Exp Med
Hlavní autoři: Singh, Kamini, Lin, Jianan, Zhong, Yi, Burčul, Antonija, Mohan, Prathibha, Jiang, Man, Sun, Liping, Yong-Gonzalez, Vladimir, Viale, Agnes, Cross, Justin R., Hendrickson, Ronald C., Rätsch, Gunnar, Ouyang, Zhengqing, Wendel, Hans-Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605752/
https://ncbi.nlm.nih.gov/pubmed/31142587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181726
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