c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma

The oncogenic c-MYC (MYC) transcription factor has broad effects on gene expression and cell behavior. We show that MYC alters the efficiency and quality of mRNA translation into functional proteins. Specifically, MYC drives the translation of most protein components of the electron transport chain...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Singh, Kamini, Lin, Jianan, Zhong, Yi, Burčul, Antonija, Mohan, Prathibha, Jiang, Man, Sun, Liping, Yong-Gonzalez, Vladimir, Viale, Agnes, Cross, Justin R., Hendrickson, Ronald C., Rätsch, Gunnar, Ouyang, Zhengqing, Wendel, Hans-Guido
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605752/
https://ncbi.nlm.nih.gov/pubmed/31142587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181726
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki