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Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis
Streptococcus pyogenes (Group A streptococcus; GAS) is a human pathogen causing diseases from uncomplicated tonsillitis to life-threatening invasive infections. GAS secretes EndoS, an endoglycosidase that specifically cleaves the conserved N-glycan on IgG antibodies. In vitro, removal of this glycan...
Guardat en:
| Publicat a: | J Exp Med |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605743/ https://ncbi.nlm.nih.gov/pubmed/31092533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190293 |
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