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IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis
Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (Pr3) are considered pathogenic in ANCA-associated necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. Modulation of ANCA IgG glycosylation may potentially reduce its pathogenic...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Nephrology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152232/ https://ncbi.nlm.nih.gov/pubmed/20448018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090984 |
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