IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis

Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (Pr3) are considered pathogenic in ANCA-associated necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. Modulation of ANCA IgG glycosylation may potentially reduce its pathogenic...

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Détails bibliographiques
Auteurs principaux: van Timmeren, Mirjan M., van der Veen, Betty S., Stegeman, Coen A., Petersen, Arjen H., Hellmark, Thomas, Collin, Mattias, Heeringa, Peter
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2010
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152232/
https://ncbi.nlm.nih.gov/pubmed/20448018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090984
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