Streptococcus pyogenes evades adaptive immunity through specific IgG glycan hydrolysis

Streptococcus pyogenes (Group A streptococcus; GAS) is a human pathogen causing diseases from uncomplicated tonsillitis to life-threatening invasive infections. GAS secretes EndoS, an endoglycosidase that specifically cleaves the conserved N-glycan on IgG antibodies. In vitro, removal of this glycan...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Naegeli, Andreas, Bratanis, Eleni, Karlsson, Christofer, Shannon, Oonagh, Kalluru, Raja, Linder, Adam, Malmström, Johan, Collin, Mattias
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605743/
https://ncbi.nlm.nih.gov/pubmed/31092533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190293
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker