Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold

G-protein coupled receptors (GPCRs) constitute major drug targets due to their involvement in critical biological functions and pathophysiological disorders. The leading challenge in their structural and functional characterization has been the need for a lipid environment to accommodate their hydro...

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Detalles Bibliográficos
Publicado en:MAbs
Main Authors: Koksal, Adem C., Pennini, Meghan E., Marelli, Marcello, Xiao, Xiaodong, Dall’Acqua, William F.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
Assuntos:
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601569/
https://ncbi.nlm.nih.gov/pubmed/30900513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596703
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