Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold

G-protein coupled receptors (GPCRs) constitute major drug targets due to their involvement in critical biological functions and pathophysiological disorders. The leading challenge in their structural and functional characterization has been the need for a lipid environment to accommodate their hydro...

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Bibliografiske detaljer
Udgivet i:MAbs
Main Authors: Koksal, Adem C., Pennini, Meghan E., Marelli, Marcello, Xiao, Xiaodong, Dall’Acqua, William F.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601569/
https://ncbi.nlm.nih.gov/pubmed/30900513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596703
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