Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold

G-protein coupled receptors (GPCRs) constitute major drug targets due to their involvement in critical biological functions and pathophysiological disorders. The leading challenge in their structural and functional characterization has been the need for a lipid environment to accommodate their hydro...

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Bibliografische gegevens
Gepubliceerd in:MAbs
Hoofdauteurs: Koksal, Adem C., Pennini, Meghan E., Marelli, Marcello, Xiao, Xiaodong, Dall’Acqua, William F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
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Report
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601569/
https://ncbi.nlm.nih.gov/pubmed/30900513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1596703
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