A novel antibody discovery platform identifies anti-influenza A broadly neutralizing antibodies from human memory B cells

Monoclonal antibody isolation directly from circulating human B cells is a powerful tool to delineate humoral responses to pathological conditions and discover antibody therapeutics. We have developed a platform aimed at improving the efficiencies of B cell selection and V gene recovery. Here, memor...

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Pubblicato in:MAbs
Autori principali: Xiao, Xiaodong, Chen, Yan, Varkey, Reena, Kallewaard, Nicole, Koksal, Adem C., Zhu, Qing, Wu, Herren, Chowdhury, Partha S., Dall'Acqua, William F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968088/
https://ncbi.nlm.nih.gov/pubmed/27049174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1170263
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