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Amber suppression coupled with inducible surface display identifies cells with high recombinant protein productivity

Cell line development (CLD) for biotherapeutics is a time‐ and resource‐intensive process requiring the isolation and screening of large numbers of clones to identify high producers. Novel methods aimed at enhancing cell line screening efficiency using markers predictive of productivity early in the...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Chakrabarti, Lina, Zhuang, Li, Roy, Gargi, Bowen, Michael A., Dall’Acqua, William F., Hawley‐Nelson, Pam, Marelli, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590230/
https://ncbi.nlm.nih.gov/pubmed/30536645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26892
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