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Amber suppression coupled with inducible surface display identifies cells with high recombinant protein productivity

Cell line development (CLD) for biotherapeutics is a time‐ and resource‐intensive process requiring the isolation and screening of large numbers of clones to identify high producers. Novel methods aimed at enhancing cell line screening efficiency using markers predictive of productivity early in the...

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Publicat a:Biotechnol Bioeng
Autors principals: Chakrabarti, Lina, Zhuang, Li, Roy, Gargi, Bowen, Michael A., Dall’Acqua, William F., Hawley‐Nelson, Pam, Marelli, Marcello
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590230/
https://ncbi.nlm.nih.gov/pubmed/30536645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26892
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