Izvoz končan — 

A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children

Recently a framework was presented to assess whether pediatric covariate models for clearance can be extrapolated between drugs sharing elimination pathways, based on extraction ratio, protein binding, and other drug properties. Here we evaluate when a pediatric covariate function for midazolam clea...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:AAPS J
Main Authors: Brussee, Janneke M., Krekels, Elke H. J., Calvier, Elisa A. M., Palić, Semra, Rostami-Hodjegan, Amin, Danhof, Meindert, Barrett, Jeffrey S., de Wildt, Saskia N., Knibbe, Catherijne A. J.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597607/
https://ncbi.nlm.nih.gov/pubmed/31250333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-019-0351-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki