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Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice
Phosphorylation of dynamin-related protein 1 (Drp1) represents an important regulatory mechanism for mitochondrial fission. Here, we established the role of Drp1 serine 600 (Drp1S600) phosphorylation in mitochondrial fission in vivo and assessed the functional consequences of targeted elimination of...
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| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597204/ https://ncbi.nlm.nih.gov/pubmed/31063459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127277 |
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