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Dynamin–Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy

Mitochondrial fission has been linked to the pathogenesis of diabetic nephropathy (DN). However, how mitochondrial fission affects progression of DN in vivo is unknown. Here, we report the effect of conditional podocyte–specific deletion of dynamin-related protein 1 (Drp1), an essential component of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Soc Nephrol
Prif Awduron: Ayanga, Bernard A., Badal, Shawn S., Wang, Yin, Galvan, Daniel L., Chang, Benny H., Schumacker, Paul T., Danesh, Farhad R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004662/
https://ncbi.nlm.nih.gov/pubmed/26825530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015101096
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