Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy

The regulatory roles of long noncoding RNAs (lncRNAs) in transcriptional coactivators are still largely unknown. Here, we have shown that the peroxisome proliferator–activated receptor γ (PPARγ) coactivator α (PGC-1α, encoded by Ppargc1a) is functionally regulated by the lncRNA taurine-upregulated g...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Long, Jianyin, Badal, Shawn S., Ye, Zengchun, Wang, Yin, Ayanga, Bernard A., Galvan, Daniel L., Green, Nathanael H., Chang, Benny H., Overbeek, Paul A., Danesh, Farhad R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096930/
https://ncbi.nlm.nih.gov/pubmed/27760051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87927
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