Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy

The regulatory roles of long noncoding RNAs (lncRNAs) in transcriptional coactivators are still largely unknown. Here, we have shown that the peroxisome proliferator–activated receptor γ (PPARγ) coactivator α (PGC-1α, encoded by Ppargc1a) is functionally regulated by the lncRNA taurine-upregulated g...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Long, Jianyin, Badal, Shawn S., Ye, Zengchun, Wang, Yin, Ayanga, Bernard A., Galvan, Daniel L., Green, Nathanael H., Chang, Benny H., Overbeek, Paul A., Danesh, Farhad R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096930/
https://ncbi.nlm.nih.gov/pubmed/27760051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87927
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