Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents

Podophyllotoxin has long been used as an active substance for cytotoxic activity. Fourteen novel biotinylated podophyllotoxin derivatives were designed, synthesized, and evaluated for cytotoxic activity for this study. The synthesized compounds were evaluated for cytotoxic activity in the following...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Chem
Κύριοι συγγραφείς: Zi, Cheng-Ting, Gao, Ying-Sheng, Yang, Liu, Feng, Shu-Yun, Huang, Yue, Sun, Li, Jin, Yi, Xu, Feng-Qing, Dong, Fa-Wu, Li, Yan, Ding, Zhong-Tao, Zhou, Jun, Jiang, Zi-Hua, Yuan, Sheng-Tao, Hu, Jiang-Miao
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2019
Θέματα:
Chemistry
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596340/
https://ncbi.nlm.nih.gov/pubmed/31281809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00434
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