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Synthesis and Biological Evaluation of 4β-N-Acetylamino Substituted Podophyllotoxin Derivatives as Novel Anticancer Agents

A series of novel podophyllotoxin derivatives obtained by 4β-N-acetylamino substitution at C-4 position was designed, synthesized, and evaluated for in vitro cytotoxicity against four human cancer cell lines (EC-9706, HeLA, T-24 and H460) and a normal human epidermal cell line (HaCaT). The cytotoxic...

詳細記述

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書誌詳細
出版年:Front Chem
主要な著者: Wei, Jinbao, Chen, Jinghong, Ju, Peijun, Ma, Le, Chen, Li, Ma, Weidong, Zheng, Tao, Yang, Guangyi, Wang, Yong-Xiang
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491884/
https://ncbi.nlm.nih.gov/pubmed/31106192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00253
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