Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents

Podophyllotoxin has long been used as an active substance for cytotoxic activity. Fourteen novel biotinylated podophyllotoxin derivatives were designed, synthesized, and evaluated for cytotoxic activity for this study. The synthesized compounds were evaluated for cytotoxic activity in the following...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Chem
Päätekijät: Zi, Cheng-Ting, Gao, Ying-Sheng, Yang, Liu, Feng, Shu-Yun, Huang, Yue, Sun, Li, Jin, Yi, Xu, Feng-Qing, Dong, Fa-Wu, Li, Yan, Ding, Zhong-Tao, Zhou, Jun, Jiang, Zi-Hua, Yuan, Sheng-Tao, Hu, Jiang-Miao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Chemistry
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596340/
https://ncbi.nlm.nih.gov/pubmed/31281809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00434
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