Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents

Podophyllotoxin has long been used as an active substance for cytotoxic activity. Fourteen novel biotinylated podophyllotoxin derivatives were designed, synthesized, and evaluated for cytotoxic activity for this study. The synthesized compounds were evaluated for cytotoxic activity in the following...

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Библиографические подробности
Опубликовано в: :Front Chem
Главные авторы: Zi, Cheng-Ting, Gao, Ying-Sheng, Yang, Liu, Feng, Shu-Yun, Huang, Yue, Sun, Li, Jin, Yi, Xu, Feng-Qing, Dong, Fa-Wu, Li, Yan, Ding, Zhong-Tao, Zhou, Jun, Jiang, Zi-Hua, Yuan, Sheng-Tao, Hu, Jiang-Miao
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596340/
https://ncbi.nlm.nih.gov/pubmed/31281809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00434
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