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An inducible model of human amylin overexpression reveals diverse transcriptional changes

Human Islet Amyloid Polypeptide or amylin is a neuroendocrine peptide with important endocrine and paracrine functions. Excessive production and accumulation of human amylin in the pancreas can lead to its aggregation and apoptosis of islet β-cells. Amylin has been shown to function within the centr...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Aldras, Yoseph, Singh, Sanghamitra, Bode, Katrin, Bhowmick, Diti Chatterjee, Jeremic, Aleksandar, O’Halloran, Damien M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594890/
https://ncbi.nlm.nih.gov/pubmed/30974231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.04.016
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