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An inducible model of human amylin overexpression reveals diverse transcriptional changes
Human Islet Amyloid Polypeptide or amylin is a neuroendocrine peptide with important endocrine and paracrine functions. Excessive production and accumulation of human amylin in the pancreas can lead to its aggregation and apoptosis of islet β-cells. Amylin has been shown to function within the centr...
Shranjeno v:
izdano v: | Neurosci Lett |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2019
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594890/ https://ncbi.nlm.nih.gov/pubmed/30974231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2019.04.016 |
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