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Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloidosis

Amyloidosis is a biological event in which proteins undergo structural transitions from soluble monomers and oligomers to insoluble fibrillar aggregates that are often toxic to cells. Exactly how amyloid proteins, such as the pancreatic hormone amylin, aggregate and kill cells is still unclear. Isle...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Singh, Sanghamitra, Trikha, Saurabh, Bhowmick, Diti Chatterjee, Sarkar, Anjali A., Jeremic, Aleksandar M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617755/
https://ncbi.nlm.nih.gov/pubmed/26149927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-17344-3_4
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