Cargando...
Functional proteasome complex is required for turnover of islet amyloid polypeptide in pancreatic β-cells
Human islet amyloid polypeptide (hIAPP) is the principal constituent of amyloid deposits and toxic oligomers in the pancreatic islets. Together with hyperglycemia, hIAPP-derived oligomers and aggregates are important culprits in type 2 diabetes mellitus (T2DM). Here, we explored the role of the cell...
Gardado en:
| Publicado en: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139561/ https://ncbi.nlm.nih.gov/pubmed/30012886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002414 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|