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Distinct Elements in the Proteasomal β5 Subunit Propeptide Required for Autocatalytic Processing and Proteasome Assembly

Eukaryotic 20S proteasome assembly remains poorly understood. The subunits stack into four heteroheptameric rings; three inner-ring subunits (β1, β2, and β5) bear the protease catalytic residues and are synthesized with N-terminal propeptides. These propeptides are removed autocatalytically late in...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Li, Xia, Li, Yanjie, Arendt, Cassandra S., Hochstrasser, Mark
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722473/
https://ncbi.nlm.nih.gov/pubmed/26627836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677047
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