Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm

Heart rate (HR) and HR variability (HRV), predictors of over-all organism health, are widely believed to be driven by autonomic input to the sinoatrial node (SAN), with sympathetic input increasing HR and reducing HRV. However, variability in spontaneous beating intervals in isolated SAN tissue and...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Moen, Jack M., Matt, Michael G., Ramirez, Christopher, Tarasov, Kirill V., Chakir, Khalid, Tarasova, Yelena S., Lukyanenko, Yevgeniya, Tsutsui, Kenta, Monfredi, Oliver, Morrell, Christopher H., Tagirova, Syevda, Yaniv, Yael, Huynh, Thanh, Pacak, Karel, Ahmet, Ismayil, Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591434/
https://ncbi.nlm.nih.gov/pubmed/31275103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00615
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