A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

The spontaneous rhythmic action potentials generated by the sinoatrial node (SAN), the primary pacemaker in the heart, dictate the regular and optimal cardiac contractions that pump blood around the body. Although the heart rate of humans is substantially slower than that of smaller experimental ani...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Tsutsui, Kenta, Monfredi, Oliver J., Sirenko-Tagirova, Syevda G., Maltseva, Larissa A., Bychkov, Rostislav, Kim, Mary S., Ziman, Bruce D., Tarasov, Kirill V., Tarasova, Yelena S., Zhang, Jing, Wang, Mingyi, Maltsev, Alexander V., Brennan, Jaclyn A., Efimov, Igor R., Stern, Michael D., Maltsev, Victor A., Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138244/
https://ncbi.nlm.nih.gov/pubmed/29895616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aap7608
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