A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

The spontaneous rhythmic action potentials generated by the sinoatrial node (SAN), the primary pacemaker in the heart, dictate the regular and optimal cardiac contractions that pump blood around the body. Although the heart rate of humans is substantially slower than that of smaller experimental ani...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Tsutsui, Kenta, Monfredi, Oliver J., Sirenko-Tagirova, Syevda G., Maltseva, Larissa A., Bychkov, Rostislav, Kim, Mary S., Ziman, Bruce D., Tarasov, Kirill V., Tarasova, Yelena S., Zhang, Jing, Wang, Mingyi, Maltsev, Alexander V., Brennan, Jaclyn A., Efimov, Igor R., Stern, Michael D., Maltsev, Victor A., Lakatta, Edward G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138244/
https://ncbi.nlm.nih.gov/pubmed/29895616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aap7608
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