Beat to beat Ca(2+)-dependent regulation of sinoatrial nodal pacemaker cell rate and rhythm

INTRODUCTION: Whether intracellular Ca(2+) regulates sinoatrial node cell (SANC) action potential (AP) firing rate on a beat-to-beat basis is controversial. OBJECTIVE: To directly test the hypothesis of beat-to-beat intracellular Ca(2+) regulation of the rate and rhythm of SANC. METHODS AND RESULTS:...

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Main Authors: Yaniv, Yael, Maltsev, Victor A., Escobar, Ariel L., Spurgeon, Harold A., Ziman, Bruce D., Stern, Michael D., Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208800/
https://ncbi.nlm.nih.gov/pubmed/21963899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2011.08.029
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