Spontaneous, local diastolic subsarcolemmal calcium releases in single, isolated guinea-pig sinoatrial nodal cells

Uptake and release calcium from the sarcoplasmic reticulum (SR) (dubbed “calcium clock”), in the form of spontaneous, rhythmic, local diastolic calcium releases (LCRs), together with voltage-sensitive ion channels (membrane clock) form a coupled system that regulates the action potential (AP) firing...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sirenko, Syevda G., Yang, Dongmei, Maltseva, Larissa A., Kim, Mary S., Lakatta, Edward G., Maltsev, Victor A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612473/
https://ncbi.nlm.nih.gov/pubmed/28945810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185222
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