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Diastolic Calcium Release Controls the Beating Rate of Rabbit Sinoatrial Node Cells: Numerical Modeling of the Coupling Process

Recent studies employing Ca(2+) indicators and confocal microscopy demonstrate substantial local Ca(2+) release beneath the cell plasma membrane (subspace) of sinoatrial node cells (SANCs) occurring during diastolic depolarization. Pharmacological and biophysical experiments have suggested that the...

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Autori principali: Maltsev, Victor A., Vinogradova, Tatiana M., Bogdanov, Konstantin Y., Lakatta, Edward G., Stern, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304106/
https://ncbi.nlm.nih.gov/pubmed/15041695
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