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Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues
Antimicrobial peptides (AMPs) have garnered much attention as novel therapeutic agents against infectious diseases. They exhibit antimicrobial activity through microbial membrane disruption based on their amphipathic properties. In this study, we rationally designed and synthesized a series of novel...
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| Pubblicato in: | Medchemcomm |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590335/ https://ncbi.nlm.nih.gov/pubmed/31303986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00166b |
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