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Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues
Antimicrobial peptides (AMPs) have garnered much attention as novel therapeutic agents against infectious diseases. They exhibit antimicrobial activity through microbial membrane disruption based on their amphipathic properties. In this study, we rationally designed and synthesized a series of novel...
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| Udgivet i: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6590335/ https://ncbi.nlm.nih.gov/pubmed/31303986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00166b |
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