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Development of hybrid small molecules that induce degradation of estrogen receptor‐alpha and necrotic cell death in breast cancer cells

Manipulation of protein stability with small molecules has a great potential for both basic research and clinical therapy. Recently, we have developed a series of hybrid small molecules named SNIPER (Specific and Non‐genetic IAP‐dependent Protein ERaser) that induces degradation of target proteins v...

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Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Okuhira, Keiichiro, Demizu, Yosuke, Hattori, Takayuki, Ohoka, Nobumichi, Shibata, Norihito, Nishimaki‐Mogami, Tomoko, Okuda, Haruhiro, Kurihara, Masaaki, Naito, Mikihiko
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7654239/
https://ncbi.nlm.nih.gov/pubmed/23992566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12272
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