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Design and synthesis of novel selective estrogen receptor degradation inducers based on the diphenylheptane skeleton
Estrogen receptors (ERs) are a family of nuclear receptors (NRs) that regulate physiological effects such as reproduction and bone homeostasis. It has been reported that approximately 70% of human breast cancers are hormone-dependent and ERα-positive. Recently, novel anti-breast cancer drugs based o...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072319/ https://ncbi.nlm.nih.gov/pubmed/30108709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00553e |
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