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Design and synthesis of novel selective estrogen receptor degradation inducers based on the diphenylheptane skeleton

Estrogen receptors (ERs) are a family of nuclear receptors (NRs) that regulate physiological effects such as reproduction and bone homeostasis. It has been reported that approximately 70% of human breast cancers are hormone-dependent and ERα-positive. Recently, novel anti-breast cancer drugs based o...

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發表在:Medchemcomm
Main Authors: Misawa, Takashi, Fujisato, Takuma, Kanda, Yasunari, Ohoka, Nobumichi, Shoda, Takuji, Yorioka, Momoko, Makishima, Makoto, Sekino, Yuko, Naito, Mikihiko, Demizu, Yosuke, Kurihara, Masaaki
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072319/
https://ncbi.nlm.nih.gov/pubmed/30108709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00553e
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